The impact of postbariatric hypoglycaemia on driving performance: A randomized, single‐blind, two‐period, crossover study in a driving simulator

Postbariatric hypoglycaemia (PBH) is an increasingly recognized complication of bariatric surgery, but its effect on daily functioning remains unclear. In this randomized, single-blind, crossover trial we assessed driving performance in patients with PBH. Ten active drivers PBH (eight females, age 38.2 ± 14.7 years, body mass index 27.2 4.6 kg/m2) received 75 g glucose to induce the late postprandial period and aspartame leave glycaemia unchanged, two different occasions. A simulator was driven during 10 minutes before (D0) 20 (D1), 80 (D2), 125 (D3) 140 (D4) after glucose/aspartame ingestion, reflecting expected blood (BG) increase decrease (D2) (D3, D4). Seven features indicating impaired were integrated a Bayesian hierarchical regression model assess difference ingestion. Mean standard deviation peak nadir BG 182 24 47 14 mg/dL, while stable (85 4 mg/dL). Despite lack symptom perception, significantly versus D4 (posterior probability 98.2%). Our findings suggest that negatively affects performance.